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pentobarbital will decrease the level or influence of ethotoin by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Monitor.
pentobarbital will reduce the extent or result of fruquintinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. If coadministration with reasonable CYP3A4 inducers is unavoidable, continue to administer fruquintinib at recommended dosage.
Contraindicated (one)pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can reduce panobinostat degrees by ~70% and result in cure failure.
Contraindicated (1)pentobarbital will lower the extent or outcome of lonafarnib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is a sensitive CYP3A4 substrate. Coadministration with powerful or average CYP3A4 inducers is contraindicated.
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pentobarbital will lessen the level or impact of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
benzhydrocodone/acetaminophen and pentobarbital equally enhance sedation. Prevent or Use Alternate Drug. Restrict use to individuals for whom different remedy possibilities are inadequate
pentobarbital will reduce the level or outcome of duvelisib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration with a solid CYP3A inducer decreases duvelisib region underneath the curve (AUC), which can lessen duvelisib efficacy.
pentobarbital will decrease the level or impact of tamoxifen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lessen the extent or outcome of midazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Contraindicated (one)pentobarbital will minimize the extent or outcome of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or outcome of etravirine by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.
pentobarbital will reduce the level or impact of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.